Urinary Markers of Detrusor Overactivity in Spina Bifida Patients

Rennes University Hospital134 enrolled

Overview

The purpose of this study is to assess diagnostic performance of urinary markers of detrusor overactivity (Nerve Growth Factor (NGF), Brain-Derived Neurotrophic Factor (BDNF), adenosine triphosphate (ATP), Prostaglandine E2) in detected high pressure bladder un spina bifida patients.

Study Type

OBSERVATIONAL

Enrollment

134

Conditions

Spina Bifida Multiple Sclerosis Spinal Cord Injury Overactive Bladder

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: Study arm: * Spina bifida patient * Seen consecutively in outpatient clinics * Age \> 18 years-old Control arm: * Patients with multiple sclerosis or spinal cord injury or overactive bladder * Seen consecutively in urodynamics * with lower urinary tract symptoms * Age \> 18 years-old Exclusion Criteria: * Positive urine culture * History of urologic neoplasms * History of interstitial cystitis

Locations (1)

Centre hospitalier universitaire de Rennes

Rennes, France

Outcomes

Primary Outcomes

Accuracy of urinary markers will be evaluated by area under the curve (AUC)

Time frame: through study completion, an average of 1 year

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.