The Effects of Scalp Block on Haemodynamic Response and Postoperative Pain in Posterior Fossa Surgery

Istanbul University45 enrolled

Overview

This study evaluate the effects of scalp block versus local infiltration on haemodynamic response to head pin replacement and skin incision and postoperative analgesia in posterior fossa surgery

In this study 15 patients will receive scalp block with bupivacaine, 15 patients will receive local infiltration with bupivacaine and 15 patients will receive placebo before surgery. The haemodynamic response to head pin replacement and skin incision will be recorded. Postoperatively all patients will have a patient controlled analgesia (PCA) device containing morphine (1 mg/ml) for analgesia. Visual analogue scale (VAS) for pain evaluation, sedation scores, and also postoperative morphine consumption will be evaluated and recorded.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Posterior Fossa Tumors

Interventions

BupivacaineDRUG

In the scalp block and local infiltration arms; bupivacaine %0,5 will be used.

morphine patient controlled analgesiaDRUG

End of the surgery all of the patients in 3 groups will receive morphine patient controlled analgesia (PCA) including 1mg/ml morphine. The PCA was set to administer a bolus dose of 1 mg on demand with a lockout period of 10 minutes and maximum 25 mg for 4 hours.

Eligibility

Sex: ALLMin age: 16 YearsMax age: 70 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Posterior fossa surgery * Preoperative GlasGow Coma Score: 15/15 Exclusion Criteria: * Allergy to bupivacaine * Uncontrolled hypertension * Coagulopathy * Cerebrovascular disease * Earlier craniotomy

Outcomes

Primary Outcomes

Heart rate response to head pin replacement and skin incision

heart rates (beats per minute) will be recorded before induction, before block, before head pinning, head pinning, head pin 5. and 10. minutes, skin incision

Time frame: Intraoperative

Systolic arterial pressure response to head pin replacement and skin incision

Systolic arterial pressures (mmHg) will be recorded in before induction, before block, before head pinning, head pinning, head pin 5. and 10. minutes, skin incision

Time frame: Intraoperative

Diastolic arterial pressure response to head pin replacement and skin incision

Diastolic arterial pressures (mmHg) will be recorded before induction, before block, before head pinning, head pinning, head pin 5. and 10. minutes, skin incision

Time frame: Intraoperative

mean arterial pressure response to head pin replacement and skin incision

Mean arterial pressures (mmHg) will be recorded in will be recorded before induction, before block, before head pinning, head pinning, head pin 5. and 10. minutes, skin incision

Time frame: Intraoperative

Secondary Outcomes

postoperative pain

pain scores (visual analogue score=VAS) will be evaluated.

Time frame: 30. minute, 1.,2.,6.,12.,24. hours pain scores (visual analogue score=VAS)

morphine consumption

morphine dosage used (mg) will be recorded in this time periods

Time frame: 30. minute, 1.,2.,6.,12.,24. hours

Data from ClinicalTrials.gov

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