The project is designed as a large scale, cross-sectional study. The aim of the study is to investigate the association of micro- and macrovascular function with physical fitness and body composition in primary school children.
The investigators will examine whether physical fitness, body composition and blood pressure differently affect large and small arteries in young children. Furthermore, the investigators will examine whether pulmonary dysfunction is associated with vascular disorders and if subcutaneous advanced glycation endproducts (AGE's) mediate some of the vascular alterations observed.
Study Type
OBSERVATIONAL
Enrollment
337
cross-sectional physical activity assessment and medical screeening
Bereich Sport- und Bewegungsmedizin, Abteilung Präventive Sportmedizin und Systemphysiologie
Basel, Canton of Basel-City, Switzerland
Association of arterial stiffness (pulse wave velocity) with physical fitness in primary school children
Oscillometric calculation of central pulse wave velocity.
Time frame: Through study completion, an average of 1 year.
Association of arteriolar-to-venular diameter ratio (AVR) with physical fitness in primary school children
Retinal vessel diameters by use of Static Retinal Vessel Analyzer (SVA-T).
Time frame: Through study completion, an average of 1 year.
Association of subcutaneous advanced glycation endproducts (AGEs) with body composition, blood pressure and physical fitness
Non-invasive, subcutaneous measurement of AGEs (skin autofluorescence).
Time frame: Through study completion, an average of one year.
Association of lung function (FEV1/VC) with body composition, blood pressure and physical fitness
Handheld spirometer (EasyOne Diagnostic) to measure vital capacity (VC), peak expiratory flow (PEF), forced expiratory volume (FEV1) and the ratio of FEV1/VC.
Time frame: Through study completion, an average of one year.
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