Total Body Composition in Detection of Nutrition Depletion in Head and Neck Patients

Inclusion Criteria: 1. Biopsy-proven head and neck (SCC), surgery of the primary tumor/lymph nodes is limited to incisional/excisional biopsy. 2. 2010 7th edition AJCC stage III, IVA (T4N0-2) and IVB (any T, N3). 3. Well-informed and accepted treatment of CCRT. 4. Age 20-70 years old. 5. Negative pregnancy test for women of childbearing potential. 6. Adequate hematopoietic or organ function which is amenable for chemotherapy: * A leukocyte count ≥3000/L * Platelet count ≥100,000/L. * Serum bilirubin level ≦ 1.5mg/dL * Serum creatinine level ≦1.6 mg/dL or creatinine clearance ≥ 60 mL/min/1.73 m2. * ALT/AST ≦ 3X ULN 9\. Ability to understand and willingness to be enrolled in our study and sign a written informed consent document Exclusion Criteria: 1. NPC is excluded from this study. 2. Patients have acute medical conditions (such as bacterial or viral infection or active cardiopulmonary disease) that may be incapable of having regular image study. 3. Patients are under regular steroid or hyperthyroid medications, which may have great impact on the whole body metabolism. 4. Patients are under-nutrient and they need to have regular liquid oral nutrition formulas support. 5. Patient that have dementia or pregnant. 6. Patients not expecting to comply with follow up. 7. Patient not suitable for chemotherapy. 8. Patient not suitable for MRI, such as claustrophobia, previous metal implantation, previous cardiac pacemaker implantation, inability to comply with MRI instructions and poor renal function. 9. Received barium study within a week.