Quantitative Cardiac Parametric Mapping

Medical University of South Carolina240 enrolled

Overview

The overall goal of this project is to evaluate the clinical potential of fast quantitative myocardial tissue characterization using recently emerged Cardiac Magnetic Resonance Imaging (CMR) techniques to aid the diagnosis, treatment, and follow up of patients with myocardial diseases, such as ischemic heart disease, cardiomyopathies, and myocarditis.

Study Type

INTERVENTIONAL

Allocation

Purpose

DIAGNOSTIC

Masking

NONE

Enrollment

240

Conditions

Cardiomyopathy, Myocarditis, Ischemic Heart Disease

Interventions

Cardiac Magnetic Resonance (CMR) imaging techniquesOTHER

Evaluation of clinical potential of fast quantitative myocardial tissue characterization using recently emerged CMRI techniques to aid the diagnosis, treatment, and follow up of patients with myocardial diseases.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 90 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Subject must be 18-90 years of age. * Subject must be previously diagnosed with or suspected to have one of the following conditions. * Myocardial ischemia or infarction (group 1) * Hypertrophic cardiomyopathy (group 2) * Infiltrative cardiomyopathy (group 3) * Myocarditis (group 4) * Subject must have been referred for a clinically indicated CMR. Exclusion Criteria: * Subject has any implanted device or condition in which an MR scan would be contraindicated. * Subject has an acute psychiatric disorder or is cognitively impaired. * Subject is using or is dependent on substances of abuse. * Subject is unwilling to comply with the requirements of the protocol. * Subject has previously entered this study. * Subject has an allergy against MRI contrast agents. * Subject is in acute unstable condition.

Locations (1)

Medical University of South Carolina

Charleston, South Carolina, United States

RECRUITING

Outcomes

Primary Outcomes

Clinical value of fast T1, T2, and T2* mapping of the left ventricle for the assessment of necrosis/scar, edema, and possible intramyocardial hemorrhage in patients with heart disease.

Time frame: 2 years

Central Contacts

Mark Ghent, BA

CONTACT

843-876-7148 ghent@musc.edu

Jacob Rowe, BA

CONTACT

843-876-4922 roweja@musc.edu

Data from ClinicalTrials.gov

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