A Training of the Rhythmic Skills With a Serious Game to Improve Gait and Cognitive Abilities in Parkinson's Disease

University Hospital, Montpellier35 enrolled

Overview

This project aims at assessing the opposite relation, namely the effect of a training of the general timing abilities on gait in Parkinson's disease. Timing rehabilitation will be done by the means of a serious game. Serious games are more and more used to improve the compliance and the efficacy of reeducaiton programs. Overall, we propose to test a low-cost tool for rehabilitation.

Auditory rythmic cueing is a method consisting in presenting a regular auditory stimulus (metronom or music) when someone is walking. It is known to improve gait in pathologies such as Parkinson's disease. It has also an effect on general timing abilities (e.g. tapping the beat of the music). This project aims at assessing the opposite relation, namely the effect of a training of the general timing abilities on gait in Parkinson's disease. Timing rehabilitation will be done by the means of a serious game. Serious games are more and more used to improve the compliance and the efficacy of reeducaiton programs. Overal, we propose to test a low-cost tool for rehabilitation.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Parkinson Disease

Interventions

Rhythm workers training Perceptive timingOTHER

Perceptive timing training

Rhythm workers training sensorimotor timingOTHER

Sensorimotor timing training

No Rhythm workers trainingOTHER

No training

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * age \< 18 * good understanding of the nature, the goal and the methodology of the study * signing of the informed consent * being insured with a social security * Diagnostic of idiopathic Parkinson's disease following the Queen Square Brain Bank (Hughes, 1992) * Hoehn et Yahr between 2 and 3 * mild to moderate walk and speech deficits (Item MDS-UPDRS) * stable therapy one month before inclusion for all the duration of the study Exclusion Criteria: * Atypic Parkinson Syndrom (oculomotor troubles, early falls, hallucinations, MoCA\<20, early dysautonomy) * dystonia ou dyskinesia preventing from using a tablet (item MDS-UPDRS4.2 \>2) * Unable to move without help (walking stick, walker, wheelchair) (item MDS-UPDRS 2.12 \>2) * adult protected by law * deprivation of liberty * High propability of non compliance to the protocol * pregnant women, nursing women * moderate to severe auditory trouble * Severe walk fluctuations item MDS-UPDRS 4.4 \>2) * Pacemaker or neurosensorial device or heart defebrillator * Cochlear implants * ferromagnetic external bodies claose to the brain * Metallic prothesis * agitated, non cooperative patient * claustrophobic patient * neuro-surgical shunt valves * dental appliance

Locations (1)

Gui de Chauliac Hospital

Montpellier, France

Outcomes

Primary Outcomes

Rythmic capacities

Evaluate the effect of the training of the rythmic capacities (Sensorimotor timing abilities) on the walk and the speak

Time frame: 3 months

Secondary Outcomes

cognitive functions

Evaluate the cognitive functions by Neurospsychologic tests

Time frame: 3 months

Mesure of the neural reorganisation

Evaluate the structure et connectivity by MRI

Time frame: 3 months

Data from ClinicalTrials.gov

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