Functional Prognosis in Patients With Ischemic Stroke According to the Therapeutic Strategy Used

Centre Hospitalier Universitaire Dijon821 enrolled

Overview

The current management of ischemic stroke is based on different strategies that may be combined: intravenous thrombolysis in a stroke ICU, intravenous thrombolysis in a telemedicine procedure, endovascular thrombectomy. Given this now rich therapeutic arsenal, it seems necessary to evaluate practices in local care in the field and the impact of these on the prognosis of ischemic stroke victims. The aim of this observational study is to compare these different care practices without interfering with the choice of strategy. A blood sample will also be taken at different times to study the value of growth differentiation factors (GDF) 8, 11 and 15, and Brain-derived Neurotrophic Factor as prognostic biomarkers

Study Type

INTERVENTIONAL

Allocation

Purpose

PREVENTION

Masking

NONE

Enrollment

821

Conditions

Ischemic Stroke

Interventions

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients with symptomatic ischemic stroke defined according to WHO criteria and treated by intravenous thrombolysis at the stroke ICU at Dijon CHU, intravenous thrombolysis by telemedicine with subsequent transfer to the Dijon stroke ICU, and/or endovascular thrombectomy at Dijon CHU) * Patients aged over 18 years. * Patients who have provided written informed consent to take part in the study. Exclusion Criteria: * Patients who refuse to take part in the study. * Subjects in custody. * Patients (or a person of trust) who cannot be contacted by telephone during the follow-up.

Outcomes

Primary Outcomes

Rate of handicap

Time frame: 6 months

Secondary Outcomes

Serum levels of biomarkers of stress

Time frame: Changes compared with baseline levels at Day 1, Day 3, Day 7