The purpose of this study is to gather data on patients diagnosed with and treated for classical Hodgkin Lymphoma (cHL). It aims to closely observe how treatment for cHL is rendered, as well as assess the outcome of those treatment options and their impact on quality of life. Additional analyses will also attempt to identify prognostic or predictive biomarkers
Study Type
OBSERVATIONAL
Enrollment
290
Norton Cancer Institute
Louisville, Kentucky, United States
Composite of Treatment Patterns
What are the treatment patterns of therapies used to treat cHL (ie, incorporation of novel chemotherapy or non-chemotherapy to upfront therapy, chemotherapy/radiation and/or transplant sparring patterns, incorporation of immune checkpoint agents or other investigational therapies)
Time frame: Up to five years
Overall Survival (OS)
Time frame: Up to five years
Progression Free Survival (PFS)
Time frame: Up to five years
Duration of Response
Time frame: Up to five years
Percentage of patients who achieve complete response
Time frame: Up to 5 years
Percentage of patients who achieve partial response
Time frame: Up to 5 years
Health-related quality of life (HRQoL)
Time frame: Up to five years
Functional Assessment of Cancer Therapy-Lymphoma (FACT-Lym)
Time frame: Up to five years
Drivers of Treatment Choice
What are drivers of choice (eg. lack of response, safety, cost or other barriers to care) for: treatment decisions across and between drug classes, changes and/or discontinuation in treatment, determinants of transplant eligibility/in-eligibility?
Time frame: Up to five years
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Healthcare resource utilization measured by imputed costs
Time frame: Up to five years
Grade of AE
Time frame: Up to 5 years