The purpose of this study is to define a reference population for FDG-PET neurological examinations starting from patients having FDG-PET to supervise a non-complicated lymphoma (tumor in remission, low disabling chronic tumor).
This study will also check normality of cerebral functions in this population and analyse the influence of various variation factors, such as age, sex ratio, education level, professional activity and neuropsychological test results on normal data. This database could be later used as comparison to patient images defining the gravity and localization of their cerebral functional disorders.
Study Type
INTERVENTIONAL
Allocation
NA
Masking
NONE
Enrollment
100
FDG injection followed by cerebral examination with X ray spiral CT after 40 minutes and FDG-PET after 60 minutes
Service de Médecine Nucléaire, Hôpital Central
Nancy, France
Absence of neurological impairment detected during standard neurological examination
Time frame: Day 0
Mini-mental state score
Time frame: Day 0
Frontal Assessment Battery score
Time frame: Day 0
Mini International Neuropsychiatric Interview (DSM-IV) score
Time frame: Day 0
Montgomery-Åsberg depression rating scale
Time frame: Day 0
Absence of cerebral abnormalities detected with PET
Time frame: Day 0
Absence of cerebral abnormalities detected with X ray spiral CT
Time frame: Day 0
Instrumental Activities of Daily Living evaluation
Evaluation of the normality of cerebral function in study population
Time frame: Day 0
Cerebral FDG distribution
Voxel-based analysis with SPM software of PET data
Time frame: Day 0
FDG mean activity in cerebral sections
Automatic measurement of FDG mean fixation in cerebral sections with NeurogamTM (Segami) software in PET data
Time frame: Day 0
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