Dual Transversus Abdominis Plane Block in Pediatric Renal Transplant: Effect on Pain Control

Cairo University44 enrolled

Overview

Alleviating pain in children undergoing renal transplant is extremely challenging. Large incisions as those of renal transplant (Gibson's incision) require special techniques of pain control that don't affect hemodynamics or renal function. Since the transplant incision doesn't cross midline; a dual-TAP block is thought to be effective in providing pain control in such procedure as it will anesthetize the dermatomes T6-T12, the muscles of the anterior abdominal wall together with the underlying parietal peritoneum.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

OTHER

Masking

NONE

Enrollment

Conditions

Renal Failure

Interventions

bupivacaineDRUG

bupivacaine 0.25% at a dose 2 mg/kg in the transversus abdominis plane

PethidineDRUG

pethidine intravenous at a dose 1mg/kg when pain score more than 5 postoperative rescue analgesia

perfalganDRUG

intravenous paracetamol

Eligibility

Sex: ALLMin age: 3 YearsMax age: 16 Years

Medical Language ↔ Plain English

Inclusion Criteria: * 3-16 years * end stage renal disease * no known allergy to bupivacaine * both sexes Exclusion Criteria: * known allergy to bupivacaine

Locations (1)

Faculty of medicine, Cairo University

Cairo, Egypt

Outcomes

Primary Outcomes

total dose of rescue analgesia

pethidine given as rescue analgesia postoperative.

Time frame: from the time of transfer of the patient to the intensive care unit at one hour intervals for 24 hours

Secondary Outcomes

pain scoring system (objective behavioural pain score)

Time frame: from the time of transfer to the nephrology ICU, every hour for the first 24 hours postoperative

Intraoperative blood pressure

measure systolic and diastolic blood pressure

Time frame: from the induction of anesthesia till end of surgery at half an hour intervals average duration is 4 hours

postoperative blood pressure

record systolic and diastolic blood pressure every hour for the first 24 hours postoperative

Time frame: from the time of transfer of the patient to the intensive care unit at one hour intervals for 24 hours

postoperative heart rate

Time frame: from the time of transfer of the patient to the intensive care unit at one hour intervals for 24 hours

intraoperative heart rate

Time frame: from the induction of anesthesia till end of surgery at half an hour intervals average duration is 4 hours

Data from ClinicalTrials.gov

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