Kinetics of Plasma and Serum Levels of Brain-Derived Neurotrophic Factor (BDNF) in Patients With Ischemic Stroke

Inclusion Criteria: * Patients (or their person of trust in cases of inability) who have been informed about the research and given their consent to take part * Patients aged 18 years or older * Patients who have suffered a de novo recent ischemic stroke \< 12 hours * Patients who had cerebral imaging (CT-Scan or MRI) * Ischemic stroke severity, measured by the National Institute of Health Stroke Score (NIHSS), between 4 and 20 Exclusion Criteria: Patients without national health insurance cover * Patients with a clinical history of stroke * Patients with cerebral or sub-arachnoid haemorrhage * Patients with a transient ischemic attack * Time of symptom onset unknown * Patients with severe aphasia at the time of the ischemic stroke defined by a sub-score for item 9 (best language) of the NIHSS ≥ 2 * Patients with dementia prior to the ischemic stroke * Patients with a significant loss of autonomy prior to the ischemic stroke, defined by a Rankin score ≥ 4 * Patients with aphasia before the ischemic stroke * Patients with a contra-indication for cerebral MRI * Pregnant or breast-feeding women * Adults under guardianship * Subjects in custody * Patients who do not speak French