In this study the investigators will determine whether the use of High Flow Nasal Cannula Oxygen during test enhances exercise performance in COPD patients on a treadmill.
Design: interventional, crossover, randomized. The main goal of this study is to compare the maximum speed reached in an Incremental Load Treadmill Test (ILTT) and max time tolerated in a Constant Treadmill Load Test (CTLT) while using High Flow Nasal Cannula Oxygen (HFNCO). Patients will be evaluated through two different kinds of tests: Incremental Load Treadmill Test (ILTT) and Constant Treadmill Load Test (CTLT). Each test will be conducted two times, once using High Flow Nasal Cannula Oxygen and the other breathing room air. In total, each patient will be evaluated four times on four different visits. The testing order will be randomized through STATA. The following variables will be measured before, during and after each test: Max speed reached in an Incremental load test: Km/h Max time tolerate in a Constant Load Test: in seconds Oxygen saturation: % Dyspnea: Modified Borg scale (0-10) Cardiac rate: beats per minute Respiratory rate: breaths per minute Blood pressure: mmHg Lower limbs fatigue: modified Borg scale (0-10) Global comfort according to the device used: visual analogue scale (VAS) 0-10
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
28
Exercise capacity testing according to High Flow Nasal Cannula Oxygen at 21% in COPD patients involved in a Pulmonary Rehabilitation program.
Exercise capacity testing in COPD patients involved in a Pulmonary Rehabilitation Program.
Hospital Italiano de Buenos Aires
Buenos Aires, Argentina
Difference in Exercise capacity - Maximun Walking Time Tolerated
Difference in Maximun Walking time tolerated in a Constant Treadmill Load Test (CTLT) in seconds between HFNCO and Room air
Time frame: Baseline and 48 hs after baseline
Difference in Dyspnea
Difference in dyspnea using Modified Borg Scale (0 - 10 points) between HFNCO and Room air
Time frame: Baseline and 48 hs after baseline
Difference in Cardiac Rate
Difference in Cardiac Rate (beats per minute) using a pulse oximetry between HFNCO and Room air
Time frame: Baseline and 48 hs after baseline
Difference in Oxygen Saturation
Difference in Oxygen Saturation using a pulse oximetry (SpO2) between HFNCO and Room air
Time frame: Baseline and 48 hs after baseline
Difference in Global Comfort
Difference in global comfort according to the device used with visual analogue scale (VAS) 0-10 between HFNCO and Room air
Time frame: Baseline and 48 hs after baseline
Difference in Lower Limbs Fatigue
Difference in Lower limbs fatigue using modified Borg scale (0-10) between HFNCO and Room air
Time frame: Baseline and 48 hs after baseline
Difference in Respiratory Rate
Difference in Respiratory rate in breaths per minute between HFNCO and Room air
Time frame: Baseline and 48 hs after baseline
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Difference in Blood Pressure
Difference in of Blood pressure in mmHg between HFNCO and Room air
Time frame: Baseline and 48 hs after baseline
Difference in Exercise capacity - Maximun Walking Speed Reached
Difference in Maximun walking speed in km/h reached in an Incremental load treadmill test (ILTT) between HFNCO and Room air
Time frame: Baseline and 48 hs after baseline