Perception of Objects and Natural Scenes in People With Vision Loss (ACTIVIS)

Lille Catholic University260 enrolled

Overview

The loss of central vision causes difficulty not only in reading but also in faces recognition, and in particular in the identification of facial expression, objects or spaces. These visual deficits have been mainly studied in relation with reading, which is the main complaint of these kind of patients. However, there are not enough data regarding perception of objects and spaces in this population. Then, the objectives are to study the visual-spatial abilities in individuals with vision loss, and altered cognitive processes, (2) to develop clinics tools for early detection and quantification of visual-spatial deficits and (3)to understand the capacities of normal peripheral vision in order to test the possibility of potential training for use of peripheral vision when central vision is impaired by an ophthalmic pathology.

Study Type

OBSERVATIONAL

Enrollment

260

Conditions

Vision Loss

Interventions

vision testsOTHER

Eligibility

Medical Language ↔ Plain English

Inclusion Criteria cases: * Patients with eye disease causing loss of central or peripheral vision * French speakers * Age between 18 and 90 years old * Written consent * Health insurance Inclusion Criteria controls: * Sex and age matched controls (+/- 5 years) * French speakers * Normal visual examination with visual acuity of min 9/10 Exclusion Criteria: * Psychiatric disease or neurological pathologies * Communication difficulties (deafness / mutism) * Drug treatment altering concentration * Mental deterioration with MMS \<24 * Alcoholism or addiction to drugs * Persons under guardianship

Outcomes

Primary Outcomes

Comparison of performances in visual tests between different groups according to error rate

These behavioral studies include a series of short tests of 5 to 10 minutes each (not exceeding 60 minutes with breaks and instructions) in which photos of scenes or isolated objects will be presented in central or peripheral vision using a computer screen or a panoramic screen covering a 180° field.

Time frame: at inclusion

Comparison of performances in visual tests between different groups according to answer time

Time frame: at inclusion

Secondary Outcomes

Estimation of the score of visual acuity by the logMAR chart

Time frame: at inclusion

Measure of lesion size

Time frame: at inclusion

Pearson correlation coefficient to determine the correlation between the performance parameters during visual tests (error rate and answer time) and clinical parameters (visual acuity and lesion size)

Time frame: at inclusion