Evaluation of the Attitude of Pre Menopausal Women With Breast Cancer Faced With the Risk of Fertility Loss Caused by Chemotherapy

Latin American Cooperative Oncology Group343 enrolled

Overview

To evaluate the attitude of pre menopausal women with breast cancer faced with the risk of loss of fertility caused by chemotherapy using EORTC's Fertility Questionnaire.

To characterize the attitude of pre menopausal patients with breast cancer regarding the risks of infertility based on the following variables: * Age at diagnosis * Number of children * Will of having children * Marital status * Scholarity * Period of time from the diagnosis * Time of the last menstruation period * Chemotherapy administration * Clinical staging at the diagnosis * Pathological evaluation * Documentation of the cancer therapy

Study Type

OBSERVATIONAL

Enrollment

343

Conditions

Breast Cancer Fertility

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 40 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Women with age ≥ 18 and ≤ 40 * Indication of (neo) adjuvant chemotherapy * Prior chemotherapy treatment * Patients with menstrual periods in the last 6 months * In use of contraceptive methods * Without breast cancer recurrence * Capacity to read and understand the informed consent Exclusion Criteria: * Patients which received or with indication of definitive ovarian suppression (surgery and/or radiotherapy), except temporary pharmacological ovarian suppression * Patients whom initiated chemotherapy treatment before entering the study * Altered state of mind, dementia, or any other psychiatry problem that can interfere in the comprehension or interpretation of the informed consent. * Previous diagnosis of infertility

Locations (7)

CPO - Pucrs

Porto Alegre, Rio Grande do Sul, Brazil

HCPA

Porto Alegre, Rio Grande do Sul, Brazil

Hospital Pérola Byington

São Paulo, Brazil

Instituto Nacional de Oncologia y Radiobiologia

Havana, Cuba

Outcomes

Primary Outcomes

To analyze the number of pre-menopausal patients diagnosed with breast cancer that did not agree in receiving chemotherapy due to the risk of infertility

Time frame: Baseline and 1 year after after the first interview

Secondary Outcomes

Infertility risk for breast cancer patients after accepting chemotherapy

Time frame: Baseline and 1 year after the first interview

Minimal percentage of cure necessary for patients accept the chemotherapy treatment

Time frame: Baseline and 1 year after the first interview

Age when diagnosed

Time frame: Baseline and 1 year after the first interview

Number of children

Time frame: Baseline and 1 year after the first interview

Desire to have kids

Time frame: Baseline and 1 year after the first interview

Marital status

Time frame: Baseline

Scholarity

Time frame: Baseline

Period of time since the diagnosis

Time frame: Baseline

Chemotherapy scheme administration

Time frame: Baseline and 1 year after the first interview

Period of time from the last menstruation period

Time frame: Baseline and 1 year after the first interview

Data from ClinicalTrials.gov

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