This study is being done to evaluate the outcomes of patients undergoing total knee replacement with two different methods of local pain control:shots of liposomal bupivacaine, a long acting anesthetic, directly into the knee during surgery or anesthetic delivered continuously to the adductor canal to provide long term pain relief. The goal is to try to find a standard protocol that provides the greatest pain relief for patients undergoing total knee replacement.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
63
Texas Orthopedics
Austin, Texas, United States
Length of stay (LOS, in days)
Time frame: Participants will be followed for the duration of their hospital stay, an expected average of 1.5 days
Time to ambulation (in hours)
Time frame: 2-6 hours
Pain as assessed by visual analog scale (VAS) on postoperative day 0
Pain levels will be determined on postoperative day 0, 1, 2, 3, 4, and 5
Time frame: 6 hours
Pain as assessed by visual analog scale (VAS) on postoperative day 1
Pain levels will be determined on postoperative day 0, 1, 2, 3, 4, and 5
Time frame: 24 hours
Pain as assessed by visual analog scale (VAS) on postoperative day 2
Pain levels will be determined on postoperative day 0, 1, 2, 3, 4, and 5
Time frame: 48 hours
Pain as assessed by visual analog scale (VAS) on postoperative day 3
Pain levels will be determined on postoperative day 0, 1, 2, 3, 4, and 5
Time frame: 72 hours
Pain as assessed by visual analog scale (VAS) on postoperative day 4
Pain levels will be determined on postoperative day 0, 1, 2, 3, 4, and 5
Time frame: 96 hours
Pain as assessed by visual analog scale (VAS) on postoperative day 5
Pain levels will be determined on postoperative day 0, 1, 2, 3, 4, and 5
Time frame: 120 hours
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Opioid consumption in oral morphine equivalents (OMEs, in milligrams)
Time frame: Participants will be followed for the duration of their hospital stay, an expected average of 1.5 days.
Postoperative complications and adverse events
Time frame: 2 weeks