This is a multi-centre study in Singapore nursing homes, investigating the factors that affecting deprescribing, and if a team-care based deprescribing standard practice gives superior health and pharmacoeconomic outcomes over current medication review practice.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
HEALTH_SERVICES_RESEARCH
Masking
SINGLE
Enrollment
295
Beers criteria 2015, STOPP criteria 2014, drug interaction
Nursing homes
Singapore, Singapore
Change from baseline in Fall Risk Assessment Tool (FRAT) score
Time frame: Change from baseline in FRAT score at 3 months
Change from baseline in Fall Risk Assessment Tool (FRAT) score
Time frame: Change from baseline in FRAT score at 6 months
Change from baseline in Fall Risk Assessment Tool (FRAT) score
Time frame: Change from baseline in FRAT score at 12 months
Change from baseline in fall rate
Time frame: Change from baseline in fall rate at 3 months
Change from baseline in fall rate
Time frame: Change from baseline in fall rate at 6 months
Change from baseline in fall rate
Time frame: Change from baseline in fall rate at 12 months
Factors affecting deprescribing
Interview questionnaire
Time frame: 0 month
Change from baseline in mean number of medications per subject
Time frame: Change from baseline in mean number of medications per subject at 3 months
Change from baseline in mean number of medications per subject
Time frame: Change from baseline in mean number of medications per subject at 6 months
Change from baseline in mean number of medications per subject
Time frame: Change from baseline in mean number of medications per subject at 12 months
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Change from baseline in mean medication cost per subject
Time frame: Change from baseline in mean medication cost at 3 months
Change from baseline in mean medication cost per subject
Time frame: Change from baseline in mean medication cost at 6 months
Change from baseline in mean medication cost per subject
Time frame: Change from baseline in mean medication cost at 12 months
Change from baseline in deprescribing intervention acceptance rate
Time frame: Change from baseline in deprescribing intervention acceptance rate at 3 months
Change from baseline in deprescribing intervention acceptance rate
Time frame: Change from baseline in deprescribing intervention acceptance rate at 6 months
Change from baseline in deprescribing intervention acceptance rate
Time frame: Change from baseline in deprescribing intervention acceptance rate at 12 months
Change from baseline in percentage of drug-related problems (DRPs)
Medication review form (Hepler/Strand DRP classification system)
Time frame: Change from baseline in percentage of DRPs at 3 months
Change from baseline in percentage of drug-related problems (DRPs)
Medication review form (Hepler/Strand DRP classification system)
Time frame: Change from baseline in percentage of DRPs at 6 months
Change from baseline in percentage of drug-related problems (DRPs)
Medication review form (Hepler/Strand DRP classification system)
Time frame: Change from baseline in percentage of DRPs at 12 months