Evaluation of a Pilot Program to Introduce Cholera Vaccine in Haiti as Part of Global Cholera Control Efforts

Inclusion criteria for cholera cases: * Seeks treatment for acute non-bloody diarrhea (defined as 3 or more loose, watery or liquid stools in a 24-hour period with an onset of 3 days or fewer prior to presentation) at a participating study site * Diarrhea episode is diagnosed as cholera, confirmed by Crystal VC rapid test and culture * Resident of Bocozel or Grande Saline at the time of study initiation * Was eligible for the vaccination campaign (i.e. ≥ 12 months of age at the time of completion of the vaccine campaign, not pregnant during the vaccination campaign). Exclusion criteria for cholera cases: * \< 12 months of age at the time of completion of the cholera vaccine campaign * Pregnant at the time of the vaccination campaign Inclusion criteria for non-cholera diarrhea cases: * Seeks treatment for acute non-bloody diarrhea (as defined above) at a participating study site * Culture negative cholera by Crystal VC rapid test and culture * Resident of Bocozel or Grande Saline at the time of study initiation * Was eligible for the vaccination campaign (≥ 12 months of age at the time of completion of the vaccine campaign, not pregnant at the time of the campaign) Exclusion criteria for non-cholera diarrhea cases: * \< 12 months of age at the time of completion of the cholera vaccine campaign * Pregnant at the time of the vaccination campaign Inclusion criteria for all controls: * Did not seek treatment for diarrhea between the date that study enrollment began and corresponding case's symptom onset (defined below) * Resident of Bocozel or Grande Saline at the time of study initiation * Was eligible for the vaccination campaign (≥ 12 months of age at the time of completion of the vaccine campaign, not pregnant at the time of the vaccination campaign) Exclusion criteria for cholera controls and secondary controls: * \< 12 months of age at the time of completion of the cholera vaccine campaign * Pregnant at the time of completion of the cholera vaccine campaign