Intestinal Fatty Acid Binding Protein in Very Low Birth Weight Infants With Meconium Obstruction

Seoul National University Hospital100 enrolled

Overview

Urinary intestinal fatty acid binding protein (i-FABP), a marker of intestinal mucosal cell damage, has recently been proposed as a clinically useful measure in the early detection of necrotizing enterocolitis (NEC). However, there are no data on urinary i-FABP in meconium obstruction of prematurity (MOP). This study aimed to evaluate urinary i-FABP in MOP patient as a marker for early detection.

Study Type

OBSERVATIONAL

Enrollment

100

Conditions

Meconium Obstruction of Prematurity

Eligibility

Sex: ALLMax age: 36 Weeks

Medical Language ↔ Plain English

Inclusion Criteria: * preterm infants weighing \<1,250g Exclusion Criteria: * major congenital anomalies * perinatal asphyxia (cord pH \<7.0)

Locations (1)

Seoul National University Hospital

Seoul, South Korea

Outcomes

Primary Outcomes

Comparison of i-FABP level between the meconium obstruction group and the normal feeding advance group

Time frame: within 48 hours after birth

Data from ClinicalTrials.gov

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