Resection Versus Microwave Ablation for Resectable Colorectal Cancer Liver Metastases

Inclusion Criteria: * Diagnosis of adenocarcinoma of the colon or rectum (diagnosed at the time of colon or rectal resection or on endoscopic biopsy) with liver metastases (by liver biopsy or by history of biopsy-proven colon/rectal cancer with characteristic imaging findings): * Imaging showing typical features of colorectal cancer liver metastasis; * Cytologic/histologic diagnosis of colorectal cancer or colorectal cancer liver metastasis. * No more than 3 hepatic metastatic lesions noted on preoperative imaging * No lesion greater than 5 cm in maximal dimension * Adequate clinical condition to undergo laparoscopic or robot-assisted laparoscopic liver resection or microwave ablation as treatment for colorectal cancer liver metastases * Willing and able to give informed consent Exclusion Criteria: * Radiologic (computed tomography or magnetic resonance imaging) evidence of invasion into major portal/hepatic venous branches and no extrahepatic metastases * Evidence of recurrent disease adjacent to a previous ablation or resection site * Severe renal dysfunction (creatinine clearance of \<40 mL/min) * Pregnant or nursing women