Fibrous dysplasia is a rare bone disease which can cause pain and fractures. It has been shown that periostin is over expressed in fibrous component in patients bones ; but periostin has never been measured out in serum of patients, although it is easy to assess. This study aims to show whether serum periostin is elevated in serum of patients with fibrous dysplasia, and if it is more elevated in patients with severe forms of the disease.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
OTHER
Masking
NONE
Enrollment
65
Patients with bone fibrous dysplasia will have blood sampling to assess periostin rate in serum
Service de rhumatologie Pavillon F - Hôpital Edouard Herriot
Lyon, France
Periostin rate in serum
Time frame: At inclusion
Periostin rate in serum according to the number of fibrotic bones
Time frame: At inclusion
Periostin rate in serum in patients with severe phenotype of the disease
Time frame: At inclusion
Periostin rate in serum in patients with Mac Cune Albright syndrome
Time frame: At inclusion
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