To evaluate possible clinical effects of adipokines , ( ghrelin, resistin and adiponectin), in obese and non-obese patients with polycystic ovary syndrome (PCOS).
Seventy selected PCOS patients will be recruited for this study, and will be divided into two groups based on their body mass index (BMI): 35 obese (BMI≥ 25 kg/m2, group A), 35 non-obese (BMI\<25 kg/m2, group B). In addition, 35 healthy non-obese women (BMI\<25 kg/m2) will bw enrolled as the control (group C). Serum levels of FSH (follicle stimulating hormone), LH (luteinizing hormone), T(testosterone), glucose, insulin, adiponectin, resistin and resistin will bw detected, and compared the differences of them among three groups
Study Type
OBSERVATIONAL
Enrollment
300
Ahmed Kotb
Cairo, Cairo Governorate, Egypt
serum ghrelin level
measuring ghrelin, and ) in the three groups
Time frame: 24 hours
serum resistin level
serum resistin level in the three groups
Time frame: 24 hours
serum adiponectin level
serum adiponectin level in the three groups
Time frame: 24 hours
Glucose/Insulin ratio
fasting glucose and insulin in three groups
Time frame: 24 hours
serum testosterone level
serum testosterone level in three groups
Time frame: 24 hours after labor
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