Integrating HCV and HIV Screening During the Era of HIV Antigen Testing

Boston Medical Center200 enrolled

Overview

The objective of this proposal is to develop an optimal testing strategy for HCV and HIV in high prevalence settings, such as detoxification centers with a large proportion of young injection drug users. The latest venipuncture testing will be compared to rapid finger stick testing for HCV and HIV. Outcomes for each strategy among individuals admitted at a short-term drug detoxification center will be determined.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

DIAGNOSTIC

Masking

NONE

Enrollment

200

Conditions

HIV Hepatitis C

Interventions

QuestionnaireBEHAVIORAL

Behavioral questionnaires

Rapid finger stickPROCEDURE

HIV and HCV testing through rapid finger stick

VenipuncturePROCEDURE

HIV and HCV testing through venipuncture

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age greater or equal to 18 * All clients admitted to BTC with a history of drug or alcohol use * Individuals who self-report as being HIV and HCV non-infected within the past 6 months or having unknown status * Participants providing contact information of two family members or friends * Individuals signing a medical records release form for the referral site (Boston Medical Center) * English speaking Exclusion Criteria: * Individuals unable to provide informed consent * Individuals with a known history of HCV and/or HIV

Locations (1)

Boston Medical Center

Boston, Massachusetts, United States

Outcomes

Primary Outcomes

Number of participants who receive HCV test results

The number of participants who receive HCV test results by the time they are discharged from the detoxification center

Time frame: within 5 days (by the time of discharge from the detoxification center)

Number of participants who receive HIV test results

The number of participants who receive HIV test results by the time they are discharged from the detoxification center

Time frame: within 5 days (by the time of discharge from the detoxification center)

Secondary Outcomes

Number of participants who link to HCV care

The number of participants who are seen for an HCV visit

Time frame: by three months

Number of participants who have HCV RNA testing

The number of participants who have HCV RNA testing performed

Time frame: by three months

Number of participants who have fibrosis staging performed

The number participants who have fibrosis staging performed

Time frame: by three months

Number of participants who have HCV treatment initiated

The number participants who have HCV treatment initiated

Time frame: by six months

Number of participants who reach sustained virologic response

The number participants who reach sustained virologic response

Time frame: by twelve months

Data from ClinicalTrials.gov

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