Efficacy and Safety of GSP 301 Nasal Spray in the Treatment of Seasonal Allergic Rhinitis (SAR)

Inclusion Criteria: * Males and non-pregnant females who are 12 years of age and older. * Documented clinical history of SAR (for at least 2 years preceding the Screening Visit \[Visit 1\]) with exacerbations (clinical evidence of active symptoms) for the relevant seasonal allergen during the Fall or mountain cedar allergy seasons (e.g., ragweed or mountain cedar pollen) * A 12-hour rTNSS ≥8 out of a possible 12 and a congestion score ≥2 for the AM assessment at the Screening Visit (Visit 1). Exclusion Criteria: * Pregnant or lactating women. * History of anaphylaxis and/or other severe local reaction(s) to skin testing. * History of positive test for HIV, Hepatitis B or Hepatitis C infection. * Documented evidence of acute or significant chronic sinusitis or chronic purulent postnasal drip. * Subjects with an active pulmonary disorder or infection. * Subjects with posterior subcapsular cataracts or glaucoma * Plans to travel outside the known pollen area for the investigational site for 24 hours or longer during the last 7 days of the run-in period.