The Effect of Dan-shen Extract On Lipoprotein Associated PHospholipase A2 Levels IN Patients With Stable Angina Pectoris

Inclusion Criteria: 1. Age:18 years-75 years; 2. Written informed consent; 3. Patients with a clinical diagnosis of chronic stable angina, which fulfil one of the following conditions: 1. Symptoms that support the diagnosis of chronic angina and/or a history of an abnormal exercise response limited by angina and/or electrocardiograph (ECG) changes 2. a history of myocardial infarction and ST-T changes, 3. stenosis of more than 50 % in at least one major epicardial coronary artery, as shown by coronary angiography or computed tomography angiography, 4. Coronary heart disease confirmed by radionuclide angiocardiography; 4. Patients with moderate angina pectoris, which is defined as Grade II or III on the Canadian Cardiovascular Society Angina Grading Scale. Exclusion Criteria: 1. Patients with severe complications that would complicate the condition, as assessed by the investigator, including liver or renal dysfunction, severe cardiopulmonary dysfunction, pulmonary hypertension, chronic obstructive pulmonary disease, a history of epilepsy or cerebral haemorrhage. 2. Patients who were angina-free during the run-in period without taking any drug. 3. Patients who experienced myocardial infarction or who were classified as Grade IV on the Canadian Cardiovascular Society Angina Grading Scale within the preceding 3 months. 4. Patients with chest pain that is caused by any other disease (e.g., acute myocardial infarction, severe neurosis, menopausal syndrome or hyperthyroidism). 5. Patients with a history of drug-induced bleeding or a history of bleeding caused by warfarin. 6. Patients with a history of haematopoietic disorder. 7. Patients who have had surgery within the previous 4 weeks or who have a haemorrhagic tendency. 8. Women who are pregnant or lactating or who have a positive pregnancy test, or women who have a menstrual period at baseline. 9. Patients who are participating in other trials or who have participated in other trials within the past 3 months. 10. Patients with a history of allergy or with a known or suspected allergy to the study drug. 11. Patients with a known or suspected history of alcohol or drug abuse within the past 2 years. 12. Patients with a mental disorder. 13. Family members or relatives of the study centre staff. 14. Inability to adhere to study procedures