Electrical Impedance Tomography for Quantification of Pulmonary Edema in Acute Respiratory Distress Syndrome Patients

Sichuan Provincial People's Hospital22 enrolled

Overview

Evaluation of pulmonary edema is a key factor in monitoring and guidance of therapy in acute respiratory distress syndrome (ARDS) patients. To date, methods available at the bedside for estimating the physiologic correlate of pulmonary edema, extravascular lung water(EVLW), often are unreliable or require invasive measurements. The purpose of the this study is to develop a novel approach to reliably assess extravascular lung water by electrical impedance tomography(EIT).

Study Type

OBSERVATIONAL

Enrollment

Conditions

Acute Respiratory Distress Syndrome

Eligibility

Sex: ALLMin age: 18 YearsMax age: 85 Years

Medical Language ↔ Plain English

Inclusion Criteria: Patients will be included in this study if the following criteria have been met: 1. Males and females \> 18 years old and \<85 years old (non-pregnant, non-lactating females). 2. Patients fulfilled the Berlin diagnostic criteria of ARDS 3. Signed written informed consent has been obtained 4. Patients had monitoring system Pulse-Induced Contour Cardiac Output (PiCCO) Exclusion Criteria: 1. Females who are pregnant or lactating. 2. Patients with contraindication of EIT(Skin abrasions or wounds in the chest area.Patients with pacemakers or paced EKG rhythms.Thoracic deformity. Severe subcutaneous emphysema) 3. Patients \<18 years old or \> 85 years old 4. Patients Without monitoring system Pulse-Induced Contour Cardiac Output (PiCCO) 5. Patients with Cardiac function of grade 4 or patients with acute myocardial infarction or acute coronary syndrome

Locations (1)

Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital

Chengdu, Sichuan, China

RECRUITING

Outcomes

Primary Outcomes

Comparison between a novel EIT-based method to estimate pulmonary edema (lung water ratio-EIT ) with a conventional measurement for EVLW using trans-cardiopulmonary thermodilution technique

Time frame: once the patient was consented and enrolled

Central Contacts

Hongli He, Ph.D

CONTACT

+86-28-87393633 doctorhhl2016@126.com

Data from ClinicalTrials.gov

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