Precision Cell Immunotherapy Combined With Chemotherapy in Advanced Lung Cancer

Inclusion Criteria: 1. Age 18\~65 years old, male or female; 2. Life expectancy≥6 months; 3. ECOG score: 0-3; 4. Advanced Malignancies (lung cancer) were diagnosed by pathological or clinical physicians; 5. Enough venous channel, no other contraindications to the separation and collection of white blood cells; 6. Laboratory examination: white blood cell≥3 x 10\*9/L, blood platelet count≥60 x10\*/L,hemoglobin≥85g/L; lymphocyte count≥15%, total bilirubin≤100 mol/L; ALT and AST less than five times of the normal level; serum creatinine less than 1.5 times of the normal level； 7. Signed informed consent； 8. Women of child-bearing age must have evidence of negative pregnancy test and be willing to practice birth control after 2 weeks following the cells transfusion. Exclusion Criteria: 1. Expected Overall survival \< 6 months; 2. Patients with uncontrolled hypertension (\>160/95mmHg), unstable coronary disease (uncontrolled arrhythmias, unstable angina, decompensated congestive heart failure (\> Class II, NYHA), or myocardial infarction within 6 months. 3. Other serious diseases: nervous, mental disorders, immune regulatory diseases, metabolic diseases, infectious diseases, etc; 4. Other drugs, or other biological treatment,chemotherapy or radiotherapy are performed within a month. 5. Unable or unwilling to provide informed consent, or fail to comply with the test requirements.