The purpose of this study is to evaluate the effect of 10 sessions of anodal transcranial Direct Current Stimulation (tDCS - 1 mA) applied to left Cortex DorsoLateral PreFrontal (CDLPF) of Alzheimer's or Primary Progressive Aphasia (PPA) patients compared to the application of a placebo tDCS (sham procedure) on cognitive functions, which are evaluated at short term (1 week post-treatment) and mild term (3 weeks post-treatment). After unblinding, patients who received placebo treatment could be received active tDCS.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
52
After locating the stimulation areas, treatment will be delivered during 30-minute session. Treatment will be occur 2 session per day during 5 consecutive days. Subjects will be monitored during tDCS sessions for any side effects or adverse events.
CHU Besancon - Clinical Psychiatric Department
Besançon, France
RECRUITINGHopital Universitaire Dijon
Dijon, France
NOT_YET_RECRUITINGAssistance Publique - Hôpitaux Paris
Paris, France
RECRUITINGchange from baseline cognitive functions at 3 weeks
neuropsychological assessments include Rapid battery tests (Bereay et al., 2015)
Time frame: baseline, day 5 and 3 weeks post-tDCS
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