The purposes of this study were to investigate the prevalence and risk factors for sarcopenia in Chinese adults and elderly, and evaluate the effect of Lifestyle Modification Project (LMP) on Clinical Outcomes, Quality of Life and Cost-effectiveness Ratio.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
HEALTH_SERVICES_RESEARCH
Masking
SINGLE
Enrollment
200
The intervention is made up of nutrition supplements and dietary pattern modification, which includes whey 30g/d(plus three times every week),vitamin D 1000IU, omega-3 fatty acid (DHA1200mg and EPA 800mg)
The training program involve warm-up exercise, muscle strength training and relaxing
Lifestyle modification project is made up of multi-dimensional intensive nutritional intervention and resistance training
Peking Union Medical College Hospital
Beijing, China
RECRUITINGrelative skeletal muscle index
RSMI(Unit: kg/m2)is defined as muscle mass
Time frame: 3 months
Hand grip
HG(Unit: kg)is defined as muscle strength
Time frame: 3 months
gait speed
GP(Unit: s)is defined as physical activity level
Time frame: 3 months
quality of life on EQ-5D scale
Scores range from 0 \[worse\] to 1\[best\](Unit on a scale)
Time frame: 3 months
The rate of fracture
rate of participants with fracture due to fall(Unit: %)
Time frame: 3 months
the change of physical function on frail index
Scores range from 0 \[normal\] to 1\[unhealth\](Unit on a scale)
Time frame: 3 months
the rate of infection complication
Rate of participants with infection complication due to sarcopenia(Unit: %)
Time frame: 3 months
mortality rate
Rate of participants mortality(Unit: %)
Time frame: 3 months
medical cost on cost-effectiveness ratio
the lower cost，the higher effectiveness(Unit: %)
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The intervention involve dietary pattern modification and protein intake standardization
Time frame: 3 months