The purpose is to characterize the change of respiratory admittance induced by salbutamol inhalation in children and young adults. A variation threshold will be fixed to distinguish asthmatic and healthy subjects. This project could allow a better identification of asthmatic individuals needing a treatment, a reduction of morbidity of asthma, a reduction of unnecessary treatments administered in individuals with respiratory but not asthmatic symptoms, a better comprehension of bronchial hyperreactivity and its role in asthmatic disease.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
DIAGNOSTIC
Masking
NONE
Enrollment
177
bronchodilation obtained with 2 inhalations of salbutamol (100 µg per dose) with inhalation chamber
before and after bronchodilation
CHU de Nancy - Hôpital BRABOIS Enfants - Explorations fonctionnelles pédiatriques
Vandœuvre-lès-Nancy, France
Ventilatory mechanical impedance
Measured with Forced oscillation technique. 2 measures at basal status at 10 min interval for reproducibility and after 10 min broncodilation with salbutamol
Time frame: day 0
Thoracic gas volume
Measured with Plethysmography.
Time frame: day 0
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