Sleep-disordered Breathing and Perioperative Atrial Fibrillation in Cardiac Surgery

Michael Arzt1,200 enrolled

Overview

In patients undergoing elective coronary artery bypass grafting (CABG) surgery, coronary artery disease, sleep-disordered breathing (SDB), atrial fibrillation (AF) perioperative atrial fibrillation and complications will be assessed. The primary objective is to determine, whether SDB patients have a higher rate of Major Adverse Cardiac and Cerebrovascular Events (MACCE) within 30 days after surgery compared to those without SDB.

Study Type

OBSERVATIONAL

Enrollment

1,200

Conditions

Elective Coronary Artery Bypass Grafting (CABG) Surgery Coronary Artery Disease Sleep-disordered Breathing (SDB)Atrial Fibrillation

Interventions

Eligibility

Sex: ALLMin age: 18 YearsMax age: 85 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients undergoing elective CABG surgery at the Department of Cardiac and Thoracic Surgery, University Hospital Regensburg. * Written informed consent Exclusion Criteria: * Preoperative use of inotropes or intra aortic balloon pump * Severe obstructive pulmonary disease * Patients on oxygen therapy, nocturnal positive airway pressure support or mechanical ventilation

Outcomes

Primary Outcomes

Major Adverse Cardiac and Cerebrovascular Events (MACCE)

periprocedural and late myocardial infarction (MI), non-fatal stroke and transitory ischemic attack (TIA) as well as all-cause mortality

Time frame: 30 days

Secondary Outcomes

postoperative atrial fibrillation (POAF)

assessed by ECG

Time frame: 30 days after CABG surgery

Stroke

assessed by questionnaire

Time frame: within 1 year after CABG surgery

MACCE

assessed by questionnaire

Time frame: within 1 and 2 years after CABG surgery

Major pulmonary complications

assessed by questionnaire

Time frame: within 30 days as well as 1 and 2 years

Sleep-disordered Breathing and Perioperative Atrial Fibrillation in Cardiac Surgery

Overview

Conditions

Interventions

Eligibility

Locations (1)

Outcomes

Primary Outcomes

Secondary Outcomes

Central Contacts