The investigators conducted a comparison trial between SLED and CRRT in critically ill patients to evaluate the outcome for all cause mortality at 30 day . The secondary outcome were recovery of renal function, complications during therapy and duration of hospitalization.
The investigators performed a single center experience accumulated over 12 months since February 2009 with a continuous venovenous hemodiafiltration (CVVHDF) and hybrid technique named sustained low-efficiency dialysis (SLED). The primary end point was death from any cause by day 30. Intensive care unit (ICU) patients were eligible for inclusion when serum creatinine was \> 2 mg/dL, and renal replacement therapy (RRT) was initiated. The selected patients were treated with CVVHDF or SLED.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
27
Slow dialysis 4 times weekly 8 hours CVVHDF predilution mode
Renal Unit, BMA Medical College and Vajira Hospital
Bangkok, Thailand
All-cause mortality
ll-cause mortality at 30 days following RRT initiation
Time frame: 30 day
Numbers of patients with abnormal laboratory values
Renal function impairment
Time frame: 30 days
ICU stay
Total days in ICU
Time frame: 30 days
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