Vulvar Scarring Grading Scale for Lichen Sclerosus

Northwestern University30 enrolled

Overview

The study aims to validate a vulvar scarring grading scale for lichen sclerosus (LS).

Utilizing the vulvar disorders registry, protocol #STU00001056, the research team seeks to analyze the medical record data, including standard of care vulvar photographs, of the vulvar LS population at Northwestern Memorial Hospital (NMH) and the outpatient clinics of Northwestern Medicine (NM). These photographs will be used to develop a vulvar scarring grading scale for LS. The objective measurement of scarring severity in LS deidentified standard-of-care patient photographs will be correlated with clinical examination findings to assess validity of the grading scale. The development of an objective and standardized grading scale will assist with the longitudinal evaluation of individual disease, assessment of impact of therapy on scarring, and inform treatment modifications. Further, objective grading of scarring would also provide the opportunity to search for potential correlation between QoL scores and severity of clinical states in scarring dermatoses.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Lichen Sclerosus Lichen Sclerosus et Atrophicus

Interventions

PhotographyOTHER

Photos will be taken of the vulvar lichen sclerosus lesions.

Eligibility

Sex: FEMALEMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients seen at Northwestern Medicine Department of Dermatology and/or Department of Obstetrics and Gynecology, who were seen by Dr. Bethanee Schlosser, and/or other members of the Vulvar Mucosal Specialty Clinic team in any of their respective clinic settings and underwent complete mucocutaneous examination. * Patients with histologically confirmed vulvar LS. Exclusion Criteria: * Patients who refuse complete mucocutaneous examination. * Patients who refuse recommended diagnostic procedures. * Pregnant women or prisoners.

Locations (1)

Northwestern University Feinberg School of Medicine, Department of Dermatology

Chicago, Illinois, United States

Outcomes

Primary Outcomes

Scarring severity grading scale for vulvar lichen sclerosus

Time frame: one year

Secondary Outcomes

Correlation of severity of vulvar LS scarring, as documented at time of clinical examination and compared to scores on the LS grading scale, with the patient quality of life at the time of examination.

Time frame: one year

Data from ClinicalTrials.gov

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