This is a randomized controlled trial to assess the efficacy of a parent training program to control disruptive behaviors in children with Tourette Syndrome.
Disruptive behaviors occur in 80% of children with Tourette Syndrome, and can be more disabling than the tics themselves. The aim of this study is to assess the efficacy of a parent training program to control disruptive behaviors in children with Tourette Syndrome. In addition, social cognition will be examined in all the participants to analyze its relationship with the severity of disruptive behavior and the treatment response. 42 children with Tourette Syndrome and moderate disruptive behaviors will be randomly assigned to a 10-week Parent Training Program or a 10-week Supportive Therapy. Clinical response will be evaluated after the intervention period, and three and six months later.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
42
Hospital Clinic
Barcelona, Spain
RECRUITINGHome Situations Questionnaire (HSQ)
Parent-rated scale with 16 items designed to assess behavioral non-compliance in regular home situations. Each item is rated on a 9-point Likert-type scale ranging from 1= "mild" to 9= "severe".
Time frame: Change from baseline to week 10; 3 months follow up; 6 months follow up
Alabama Parenting Questionnaire
42-item clinical-administered questionnaire designed to measure the following dimensions of parenting style: 1- Positive involvement with children, 2- Supervision and monitoring, 3- Use of positive discipline technique, 4- Consistency in the use of such discipline and 5- Use of corporal punishment. Each item is scored on a 5-point, Likert-type scale from 1="never" to 5 = "always".
Time frame: Change from baseline to week 10; 3 months follow up; 6 months follow up
Parent Stress Index-Short Form
Parent-rated scale with 36-items questionnaire designed to measure stress in parent-child relationship.
Time frame: Change from baseline to week 10; 3 months follow up; 6 months follow up
The Gilles de la Tourette Syndrome-Quality of Life Scale (GTS-QOF)
Patient-reported scale with 27-items designed to measure health-related quality of life in children and adolescents with Tourette Syndrome.
Time frame: Change from baseline to week 10; 3 months follow up; 6 months follow up
Yale Global Tic Severity Scale (YGTSS)
Semi-structured interview to measure tic severity. After an initial inventory of current and lifetime motor and phonic tic types, current tic number, frequency, intensity, complexity and interference are rated on a 6-point scale. Maximum score is 100, resulting from three subscales: motor tic severity (maximum score 25), phonic tic severity (maximum score 25) and general impairment due to tics (maximum score 50).
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Time frame: Change from baseline to week 10; 3 months follow up; 6 months follow up