Multiple studies have compared spinal anesthetic performed supine versus lateral, with varying results, in parturients having elective cesarean section. Needle positioning during spinal placement has also been examined. No positioning techniques have demonstrated definitive superiority for hemodynamic stability. Investigators propose that following spinal placement in the sitting position if the patient is placed in a lateral position for 90 seconds prior to turning them supine, hemodynamic changes caused by sympathectomy related to the subarachnoid block can be avoided. This is the first study to examining the influence of position changes after spinal anesthetic placement in the sitting position, which includes hemodynamic variables not previously studied including cardiac output, TPR (total peripheral resistance) and pulse pressure variation (PPV).
Cesarean section is chosen when natural spontaneous vaginal delivery is either not possible or when the health of the baby or mother is compromised. Cesarean section may be planned, urgent, or performed emergently when the life of the baby or mother is threatened. Cesarean section is performed using different anesthetic techniques including: spinal, epidural, combined spinal and epidural, and general anesthesia. Spinal anesthesia is the most common technique chosen due to its relative safety, rapid onset and avoidance of potential complications from general anesthesia. It is the technique of choice for elective cesarean section unless contraindicated. Spinal anesthesia causes sympathetic blockade followed by sensory and motor blockade. Nerve fiber size explains the speed of onset and differential block. The critical moments during spinal anesthesia come as soon as local anesthetic is injected into the subarachnoid space.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Enrollment
61
Spinal anesthesia in sitting position then 2 minutes in Supine position after spinal anesthetic administration
Spinal anesthesia in sitting position then 2 minutes in the right lateral position after spinal anesthetic administration
Spinal anesthesia in sitting position then 2 minutes in the left lateral position after spinal anesthetic administration
UTMB
Galveston, Texas, United States
Heart rate
Continuous Heart rate (beats per minute) measurements.
Time frame: Immediately before spinal anesthestic placement through placental delivery
Blood pressure
Continuous Blood pressure (mmHg) measurements
Time frame: Immediately before spinal anesthetic placement through placental delivery
Incidence of nausea and vomiting
Nausea and vomiting incidence and anti-emetic administration with time stamps will be documented.
Time frame: Number of events spinal anesthetic placement through placental delivery
Anti-emetic medication
Anti-emetic administration with time stamps will be documented.
Time frame: Number of events spinal anesthetic placement through placental delivery
Incidence of vasopressor usage
Number of vasopressor use events will be monitored and recorded.
Time frame: Spinal anesthetic placement through placental delivery
Total vasopressor usage
All vasopressor administrations with time stamps will be documented.
Time frame: Spinal anesthetic placement through placental delivery
Non Invasive Cardiovascular measurements: cardiac output
Continuous Cardiac output (L/min) measurements
Time frame: Spinal anesthetic placement through placental delivery
Non Invasive Cardiovascular measurements: stroke volume
Continuous Stroke volume (mL) measurements
Time frame: Spinal anesthetic placement through placental delivery
Non Invasive Cardiovascular measurements: TPR (total peripheral resistance)
Continuous TPR (total peripheral resistance, dynes\*sec/cm3)measurements
Time frame: Spinal anesthetic placement through placental delivery
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