The purpose of this study is to evaluate the tolerance and the efficiency of subcutaneous administration of Paracetamol for patients in palliative care.
Subcutaneous administration is the most commonly used way for palliative care and geriatric service. A lot of drugs are recommended with subcutaneous administration, but their use is performed out of the Marketing Authorization, and fewer data exist about this practice in literature. Paracetamol is a grade 1 analgesic not currently recommended for subcutaneous injection, because of the lack of validated references. However this kind of administration is usually performed for Paracetamol in the French palliative care services related with its advantages for patients, as analgesic or antipyretic. The assumption of the study is that the use of paracetamol subcutaneously is possible with a good tolerance for hospitalized patients in palliative care service.
Study Type
OBSERVATIONAL
Enrollment
160
CHR Metz-Thionville
Metz, France
GH Diaconesses Croix Saint Simon
Paris, France
Occurrence of the severe or not adverse effects on the injection site
Time frame: 8 days
as antipyretic, a feedback of tympanic temperature below 38°C during the two hours after injection
Time frame: 8 days
as analgesic, the decrease of pain (decrease of 30 in the numerical scale score, or a Algo+ scale score lower than 2/5)
Time frame: 8 days
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