The Association Between Autoimmune or Inflammation and Thyroid Disease

Taichung Veterans General Hospital500 enrolled

Overview

This study aims to evaluate the effects of thyroid functions on energy homeostasis and inflammation.

The subjects were enrolled for evaluation of thyroid functions. The associations between thyroid function and energy homeostasis and inflammation will be assessed.

Study Type

OBSERVATIONAL

Enrollment

500

Conditions

THYROTOXICOSIS

Eligibility

Sex: ALLMin age: 20 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Subjects visits outpatient department due to a suspicion of thyroid disease Exclusion Criteria: * Psychological disorders, severe inflammatory or infection diseases.

Locations (1)

Division of Endocrinology and Metabolism, Department of Internal Medicine, Taichung Veterans General Hospital

Taichang, Taiwan

RECRUITING

Outcomes

Primary Outcomes

brain-derived neurotrophic factor

BDNF

Time frame: 3 months

Secondary Outcomes

vascular cell adhesion molecule 1 (VCAM-1)

Inflammation

Time frame: 3 months

C-reactive protein (CRP)

Inflammation

Time frame: 3 months

Orexin

Psychological assessment

Time frame: 3 month

Zung Self-Rating Depression Scale (Zung SDS)

Depressive symptom

Time frame: 3 month

Body composition

fat component

Time frame: 3 month

ankle brachial index (ABI)

Arterial stiffness

Time frame: 3 months

pulse wave velocity (PWV)

Arterial stiffness

Time frame: 3 months

mean arterial pressure (MAP)

Arterial stiffness

Time frame: 3 months

Central Contacts

I-Te Lee, MD

CONTACT

itlee@vghtc.gov.tw

Data from ClinicalTrials.gov

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