During surgery for pelvic organ prolapse, it is common for the surgeon to inject fluid into the vaginal tissues to help with tissue dissection. It is common that anesthetic medication is mixed into this fluid to help with pain control after surgery. Usually the pain medication injected is short-acting. In this study the investigators plan to compare the usual short-acting injected pain medication with a long-acting injected pain medication to evaluate whether this improves pain control after surgery. One type surgical procedure for prolapse will be evaluated. The procedure is sacrospinous ligament fixation. This is suspension of the vagina to treat pelvic organ prolapse. Study participants will be randomized to one of two study groups: 1. Lidocaine group (short-acting medication). 2. Liposomal bupivacaine group (long-acting medication) Information will be collected on study participants, including: demographics, procedure data, and post-operative information. The primary outcome of this study is determine if use of long-acting injected local anesthesia at the time of sacrospinous ligament fixation leads to less post-operative pain compared to short-acting local anesthesia. Secondary outcomes include: 1. post-operative opioid medication use 2. return to baseline pain status 3. post-operative time to first bowel movement 4. post-operative antiemetic use (nausea medication) 5. results of voiding trial after surgery 6. patient satisfaction with pain control
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
30
Hartford Hospital, Urogynecology Division
Hartford, Connecticut, United States
RECRUITINGVisual analog pain scale
post-operative pain
Time frame: 1 to 120 hours post-operative
Equivalents of morphine used for pain control post-operative while hospitalized
Post-operative opioid use, in hospital
Time frame: 1-2 days post-operative
Equivalents of morphine used from the time of hospital discharge to post-operative day 7
Post-operative opioid use, after hospital discharge
Time frame: 7 days post-operative
Modified surgical pain scale
Return to baseline pain status
Time frame: 3, 7, 14, 28 days post-operative
Time to first bowel movement
Days to first postoperative bowel movement
Time frame: 1-28 days post-operative
Post-operative antiemetic use, in hospital
Time frame: 1-2 days post-operative
Void trial
Results of in-hospital void trial
Time frame: 1-2 days post-operative
HCHAPS pain questionnaire
Patient satisfaction with pain control
Time frame: 48 hours post-operative
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