Effects of the Use of Platelet-rich Fibrin on Bone Regeneration After Impacted Third Molar Surgery

Rio de Janeiro State University20 enrolled

Overview

The purpose of this study is to evaluate the bone regeneration after impacted third molar surgery on split mouth design using platelet-rich fibrin.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

TRIPLE

Enrollment

Conditions

Fibrin/Therapeutic Use Blood Platelets Molar, Third Bone Regeneration

Interventions

Platelet-rich fibrinPROCEDURE

Control groupPROCEDURE

Eligibility

Sex: ALLMin age: 16 YearsMax age: 29 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Healthy patients * Preoperative platelet count higher than 150,00/ mm3 * Patient who required bilateral mandibular third molar extractions Exclusion Criteria: * Smokers patients * Alcoholics patients * Patients whom the inferior second molar was missing * Patients who had acute pericoronitis on the inferior third molar * Severe periodontal disease

Locations (1)

João Canellas

Rio de Janeiro, Rio de Janeiro, Brazil

Outcomes

Primary Outcomes

Change in bone density through tomography evaluation

Time frame: Change from Baseline bone measurement at three months after surgery

Secondary Outcomes

Change in periodontal-probing depth measurement on distal aspect of the second molar through Clinical evaluation

Time frame: Change from baseline at 3 months after surgery

Pain through Visual Analogue Scale

Time frame: 1st day after surgery

Pain through Visual Analogue Scale

Time frame: 3rd day after surgery

Pain through Visual Analogue Scale

Time frame: 7th day after surgery

Soft tissue healing through Clinical evaluation numeric scale

Time frame: 7th day after surgery

Data from ClinicalTrials.gov

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