Maternal and Neonatal Microbiome

Hadassah Medical Organization

Overview

The aim of the study is to characterize and monitor the microbiome of premature infants born in the investigators facility until discharge from the NICU. The investigators will also examine the relationship between mode of delivery and the microbiome of the infant, while exploring various possible factors that may affect it. In addition, the investigators will compare the microbiome of premature infants to the microbiome of term babies born at the same time in the same facility.

Study Type

OBSERVATIONAL

Conditions

Microbiota

Interventions

non invasive samplingOTHER

Eligibility

Sex: ALLMax age: 50 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Premature infants ≤ 34 weeks of gestation admitted to the Neonatal Intensive Care Unit at Hadassah University Hospital, Mount Scopus and their mothers. The control group: * Neonates ≥ 37 weeks gestation of which 50 were delivered vaginally and 50 by Caesarean section at Hadassah University Hospital, Mount Scopus and their mothers. Exclusion Criteria: * Neonates with congenital anomalies or metabolic conditions.

Locations (2)

Hadassah Medical Organization, Jerusalem, Israel

Jerusalem, Israel

Hadassah Medical Organization

Jerusalem, Israel

Outcomes

Primary Outcomes

Definition the flora comprising the microbiome of premature and term babies

Time frame: birth

Secondary Outcomes

Difference in the microbiome of the infants born vaginally and via caesarian section

Time frame: birth

Change in the flora that constitutes the microbiome of premature babies

Time frame: birth until adjusted age of 40 weeks gestation

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.