Deep Brain Stimulation of the Sub-Thalamic Nucleus to Treat Severe and Treatment-resistant Cocaine Addiction.

Inclusion Criteria: * severe and resistant Cocaine Dependence for 5 years defined as: * cocaine dependence (DSM IV), * preferential use of cocaine in base form (crack or free-base) through smoke, * non response to at least two well-conducted treatment with at least a stay in aftercare, * severe physical complications (defined as a history of myocardial infarction, stroke). * psychotic syndromes induced recurrent, severe lung disease "crack-lungs") occurred due to crack consumption and whose association with the crack use is known to the patient * age between 30 and 55 years * patient affiliated to a social security scheme * patient signed an informed consent after receiving written information on the proposed procedure Exclusion Criteria: * a current opioid dependence will not be a criterion of non inclusion if the patient is undergoing substitution treatment (methadone or buprenorphine) and not injection of opiates for at least six months. * patient trust * pregnant, nursing or of childbearing potential without effective contraception * current use of the intravenous route for the administration of the drugs is the risk of infection * VIH infection or VHC unstabilized, * cardiovascular and / or brain state is not compatible with the surgery, * other disorder on Axis I not linked to cocaine use except: * current or past dependence to nicotine, * abuse or dependence on other psychoactive substances over a lifetime in remission for more than 6 months, * current opioid dependence: if the patient is undergoing substitution treatment (methadone or buprenorphine) and not injection of opiates for at least 6 months, * when other psychiatric disorders induced by substances.