Intravenous Lidocaine in Carcinologic ENT Surgery: A Trial for Evaluation of Opioid Saving Strategy and Chronic Post-surgical Pain (ELICO)

Inclusion Criteria: * Patient undergoing major carcinological ENT surgery (total laryngectomy, oropharyngectomy with or without mandibulotomy, crico-hyoido-epiglotto-pexy, intraoral extended resection, partial laryngectomy, partial pharyngectomy, extended pelvectomy, pelviglossectomy, with or without pectoralis major flap or free flap, with or without lymphadenectomy) * Patient receiving standardized Patient Controlled Analgesia (PCA) * Written informed consent Exclusion Criteria: * Hypersensitivity to local anesthetics of the amide group, * Acute porphyria * Atrioventricular conduction disorders requiring permanent electro-systolic * Epilepsy not controlled by treatment * Hepatocellular insufficiency (PT\<50%) or cirrhosis * Systolic heart failure (LVEF \<50%) * Major inflation State * Hypersensitivity to any component of Glucose 5% * Treatment with beta-blockers or antiarrhythmic of Vaughan Williams classification * BMI \> 30kg/m2 * Patient already treated for chronic pain with level 3 analgesic or for neuropathic pain * Pregnant or lactating women * Refusal to give consent * Patient under legal protection measure