Preparatory Work to Assess Adherence to Oral Chemotherapy

Wake Forest University Health Sciences86 enrolled

Overview

This study to find out more about how patients take their anticancer medications and challenges related to taking cancer medications.

120 patients with Chronic Myeloid Leukemia (CML) who are currently prescribed an oral anti-cancer agent from up to 6 CCDR NCORP sites to complete a brief interviewer administered survey to assess medication adherence and related factors.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Chronic Myeloid Leukemia

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patient is diagnosed with Chronic Myeloid Leukemia (CML) and is receiving care for CML at a participating CCDR NCORP practice, * Patient had been prescribed one of the following oral anticancer agents for CML for ≥30 days (Imatinib, Nilotinib, Dasatinib, Bosutinib, Ponatinib). Prior use of any of these medications is allowed, as long as they have been on a stable regimen for at least 30 days prior to enrollment. * Patient is 18 years of age or older Exclusion Criteria: * Patient does not speak English or requires an interpreter for medical visits * Patient is cognitively impaired, as determined by the referring provider

Locations (1)

Wake Forest School of Medicine

Winston-Salem, North Carolina, United States

Outcomes

Primary Outcomes

Patient Demographic and Health Behaviors Questionnaire

Questions will be asked about the participants demographic background and health behaviors.

Time frame: Study 1 day Visit

Brief Medication Questionnaire (BMQ)

A self-report tool for screening adherence and barriers to adherence. The tool includes a 5-item Regimen Screen that asks patients how they took each medication in the past week, a 2-item Belief Screen that asks about drug effects and bothersome features, and a 2-item Recall Screen about potential difficulties remembering.

Time frame: Study 1 day Visit

Single Item Adherence Measure 1

This is a single question. This measure was developed to serve as simple means of identifying sub-optimal adherence which could help identify at-risk patients for interventions.

Time frame: Study 1 day Visit

Single Item Adherence Measure 2

This single item was developed to evaluate self-report adherence to medication and has demonstrated low patient burden and the ability to predict adherence-related clinical outcomes as good or better than other adherence measures.

Time frame: Study 1 day Visit

Secondary Outcomes

REALM-SF

The REALM-SF offers researchers a simplified, validated, and efficient instrument for assessing patient literacy in clinical setting. It can be used to investigate the relationship between literacy and specific health outcomes such as medication adherence and health care utilization.

Time frame: Study 1 day Visit

Medications Adherence Reasons Scale (MARS)

This questionnaire is designed to identify potential risk factors associated with medication-related non-adherence.

Data from ClinicalTrials.gov

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