Burnout Syndrome is one of the major challenges for health systems worldwide. This study strives to evaluate the feasibility and effectiveness of an 8- versus 2-week mindfulness-based self-care program on burnout symptoms and psychological and biological variables.
The development of stepped-care interventions allows for the development of new strategies within mindfulness-based approaches, classically described as a weekly two-hour commitment which lasts eight weeks. Such approaches might reach larger and stratified groups, more suitable for usage in Brazilian health-system context. For such evaluations, the investigators will use a 3-arms randomized clinical trial design, with Sociodemographic and Labor variables, such as age, sex, number of offspring, adherence to the program, adherence to the mindfulness practices, Burnout Clinical Subtype Questionnaire -(BCSQ-36), Maslach Burnout Inventory (MBI-GS), Mindfulness Attention Awareness Scale (MAAS), Freiburg Mindfulness Inventory adapted for Brazil (FMI-Br-13), Five-Facet Mindfulness Questionnaire (FFMQ-Br). DNA methylation will be measured by Methylase-reaction, and BDNF (brain-derived neurotrophic factor) will be quantified by ELISA-sandwich. The primary outcome will be the effectiveness of such programs on different clinical subtypes of Burnout symptoms (frenetic, under challenged and worn-out). The secondary outcome will be mindfulness levels, and adherence to the program and to the mindfulness practice, and on inflammation and epigenetic variables.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Enrollment
400
8 sessions of mindfulness
2 sessions of mindfulness
A mindfulness intervention decreases Burnout
Evaluation of Burnout symptoms through the MBI-GS scale
Time frame: up to 2 months of follow-up
A mindfulness intervention increases Happiness
Evaluation of Happiness levels through the PHI (Pemberton) scale
Time frame: up to 2 months of follow-up
A mindfulness intervention increases Mindfulness
Evaluation of Mindfulness levels through the MAAS scale
Time frame: up to 2 months of follow-up
A mindfulness intervention improves Epigenetic
Evaluation of epigenetic-related activity through Homocysteine levels (Pfeiffer, 1999)
Time frame: up to 2 months of follow-up
A mindfulness intervention improves Epigenetic (II)
Evaluation of epigenetic-related activity through Cysteine levels (Pfeiffer, 1999)
Time frame: up to 2 months of follow-up
A mindfulness intervention improves Epigenetic (III)
Evaluation of epigenetic-related activity through Methylase Reaction (Radiomarking of methyl groups)
Time frame: up to 2 months of follow-up
A mindfulness intervention improves Inflammation
Evaluation of inflammation-related activity through seric Brain-Derived Neurotrophic Factor - BDNF- (ELISA-Sandwich)
Time frame: up to 2 months of follow-up
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