The purpose of this clinical study is to evaluate the effect of a four-week consumption of a fresh fermented dairy drink containing probiotic strains on Antibiotic-Associated Diarrhea and Gastro-Intestinal disorders in adult subjects treated for Helicobacter pylori eradication.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
TRIPLE
Enrollment
136
1 - Fresh fermented dairy drink containing yoghurt ferments and probiotic strains consumed as follows: one bottle (100g) BID for 28 consecutive days (Day 0 to day 28)
2 - Acidified dairy drink without ferments consumed as follows: one bottle (100g) BID for 28 consecutive days (Day 0 to day 28)
Charité Research Organisation GmbH
Berlin, Germany
Occurrence of AAD
Time frame: From Day 0 to Day 28
Duration of AAD
Time frame: From Day 0 to Day 28
Time to event of AAD
Time frame: From Day 0 to Day 28
Occurrence of Clostridium difficile Associated Diarrhea
Time frame: From Day 0 to Day 28
Time to event of Clostridium difficile Associated Diarrhea
Time frame: From Day 0 to Day 28
Duration of Clostridium difficile Associated Diarrhea
Time frame: From Day 0 to Day 28
Number of days with main GI symptoms (diarrhea, abdominal pain, bloating, nausea, vomiting)
Time frame: From Day 0 to Day 28
Score of gastrointestinal symptoms
Time frame: From Day 0 to Day 28
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