Health Economics Evaluation of the Management of Severe Postpartum Hemorrhage: Comparison of Recombinant Activated Factor VII Strategy to the Reference Strategy

Inclusion Criteria: * Severe haemorrhage is defined by the following criteria: blood loss greater than 1500 ml graduated measured in the bag and / or hemodynamically unstable and / or requiring transfusion of packed red blood cells (3); * Sulprostone (Nalador®) ineffective; * Age over 18 years; * The term is more than 27 SA (child's viability); * Without anthropomorphic limit; * The outcome of the pregnancy is normal or pathological; * Informed consent "emergency procedure" is signed by the husband or family. Exclusion Criteria: * minors, majors in guardianship, with a personal history of venous or arterial thrombosis may cons-indicate treatment with rFVIIa or refuses to sign the consent