This randomised controlled trial aims to evaluate the difference in surgical site infection following excision of soft tissue sarcomas. The intervention is a negative wound pressure therapy dressing for 120 hours, the control is standard absorbent dressings
Hypothesis: The application of a negative pressure wound therapy (NPWT) dressing will reduce rates of wound breakdown in patients with resection of soft tissue sarcomas which are primarily closed. Patients will be randomised into either NPWT or standard absorbent dressings with primary outcome measure of surgical site infection according to the Health Protection Agency guidance. Secondary outcomes are; time to wound dryness, delayed discharge from hospital, adverse events, cost estimation
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Enrollment
17
Current absorbent dressing is 'tegaderm with absorbent pad' (3M)
Glasgow Royal Infirmary
Glasgow, Scotland, United Kingdom
Surgical Site Infection (proportion)
As diagnosed by independent observer according to the Healthcare Protection Agency (UK) guidelines
Time frame: 30 days
Time to wound dryness (nominal scale)
Time to the nearest 12 hour period by which there is no further wound exudate (e.g. staining on dressing)
Time frame: 30 days
Delay to discharge form hospital (nominal scale)
Number of additional hospital stays attributable to wound issues
Time frame: 30 days
Adverse events (count)
Number of unanticipated events
Time frame: 30 days
Cost analysis (comparative nominal scale in £)
Cost analysis to evaluate potential offset of costs for NPWT
Time frame: 30 days
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