Forced Oscillations for Diagnosis Help in Bronchiolitis Obliterans Syndrome in Post Bone Marrow Transplantation

Hopital Foch110 enrolled

Overview

A study to evaluate the role of forced oscillations in diagnosis of bronchiolitis obliterans syndrome in patients after bone marrow transplantation. The force oscillations technique will be compared with classical spirometry.

Study Type

INTERVENTIONAL

Allocation

Purpose

DIAGNOSTIC

Masking

NONE

Enrollment

110

Conditions

Bronchiolitis Obliterans Bone Marrow Transplantation

Interventions

Forced oscillations measureOTHER

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients over 18 years * Bone marrow or hematopoietic stem cells transplantation for more than 100 days * Clinical stability * Patients affiliated to a social security system * Patients having given his (her) written consent. Exclusion Criteria: * Bronchiolitis Obliterans already diagnosed * Unresolved Respiratory infection * Unresolved mechanical complication (pneumothorax, effusions) * Medicinal pneumopathy * Inability to perform pulmonary function tests

Locations (2)

CHRU de Lille

Lille, France

Hopital Foch

Suresnes, France

Outcomes

Primary Outcomes

Number of days

Temporal difference between the date of the functional change measured by the technique of the forced oscillations and by the standard techniques of plethysmography.

Time frame: 2 years

Data from ClinicalTrials.gov

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