Local Administration of Tranexamic Acid in Upper Gastrointestinal Hemorrhage

Inclusion Criteria: * Patients presenting with upper gastrointestinal hemorrhage to the ED * Patients older than 18 years * Patients who agree to participate the study by reading and signing the informed consent form Exclusion Criteria: * Patients younger than 18 years * Patients who do not agree to participate the study * Documented or declared allergy to tranexamic acid * Upper gastrointestinal hemorrhage secondary to trauma * Upper gastrointestinal hemorrhage secondary to esophageal varices * Patients who cannot undergo to endoscopy for any reason * History for thromboembolic disease * Patients with renal impairment