The purpose of the present study was to evaluate the effects of subgingival delivery of boric acid gel as an adjunct to scaling and root planing in chronic periodontitis (CP) patients.
Background: The purpose of this double-masked, randomized, controlled clinical trial was to evaluate the effects of subgingival delivery of boric acid gel as an adjunct to scaling and root planing (SRP) on clinical and radiographic parameters and compare this method with SRP plus placebo gel alone in with chronic periodontitis (CP) patients. Methods: Thirty nine systemically healthy patients with CP are included in this study. They were divided into two groups: 1) SRP + 0.75% Boric acid gel (BA group); 2) SRP + Placebo gel (Placebo group). At baseline, 3 month, and 6 months after treatment, clinical measurements, including plaque index (PI), modified sulcus bleeding index (mSBI), probing depth (PD), clinical attachment level (CAL) and radiographic parameters intrabony defect depth (IBD), percentage change in radiographic defect depth reduction (DDR%) were assessed.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
39
SRP followed by 0.75% boric acid placement into intrabony defect
SRP followed by placebo gel placement into intrabony defect
Unnamed facility
Bangalore, Karnataka, India
Defect depth reduction (%)
assessed in percentage
Time frame: Change from baseline to 6 months
probing depth (mm)
measured in mm
Time frame: Change from baseline to 6 months
clinical attachment level (mm)
measured in mm
Time frame: Change from baseline to 6 months
modified sulcus bleeding index
scale from 0-3
Time frame: Change from baseline to 6 months
plaque index
scale from 0-3
Time frame: Change from baseline to 6 months
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