The functional parathyroid auto-transplantation (PA) could release parathyroid hormone (PTH) into the circulatory system of the body through the capillaries. But when parathyroid glands were auto-grafted in the sternocleidomastoid muscle, it would be inconvenient to detect PTH to examine whether the graft functions. So the investigators took the forearm as the aim place for auto-transplantation, either subcutaneous or brachioradialis, with its relatively fixed - antecubital vein blood test which is simple. The survival criteria is assumed as the PTH gradient of 1.5 times or greater through comparing the bilateral PTH value in grafted and not-grafted forearm.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Enrollment
280
new-site for parathyroid autografting, close to the antecubital vein
traditional-site for parathyroid autografting,not intensively close to the antecubital vein
Tongji Hospital
Wuhan, Hubei, China
RECRUITINGparahthyroid hormone gradient by comparing between grafted and non-grafted forearm
The survival criteria is that the gradient of parathyroid hormone reaches 1.5 time or greater by comparing between grafted and non-grafted forearm
Time frame: 1 months, 3 months and 6 months
hypoparathyroidism: parathyroid hormone less than 15pg/ml(range from 15 to 65pg/ml)
Time frame: 6 months
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